Gene Ontology (GO) is a widely used bioinformatics resource that provides a structured vocabulary to describe the molecular functions, biological processes, and cellular components of gene products across all species. It is a powerful tool for functional annotation of genes and gene products, allowing researchers to categorize and analyze gene functions in a standardized and systematic manner. GO terms are organized in a hierarchical structure, with more specific terms being descendants of more general terms, making it easier to compare and analyze gene functions across different studies. GO annotations are widely used in genomic and transcriptomic studies to interpret biological data and generate hypotheses about gene function and gene regulatory networks.